A Transition‐Metal‐Free Synthesis of Multisubstituted Imidazoles.
2016
A novel and simple t-BuOLi/I-2-mediated synthesis of 1,2,4-trisubstituted imidazoles was developed without transition-metal added. The transition-metal-free strategy tolerated a range of substrates and provided products in moderate to good yields with 100% regioselectivity.
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