Improved pharmacokinetics and reduced side effects of doxorubicin therapy by liposomal co-encapsulation with curcumin

Alina Sesarman,Dana Muntean,Bianca Abrudan,Lucia Tefas,Bianca Sylvester,Emilia Licarete,Valentin-Florian Rauca,Lavinia Lupuţ,Laura Pătraş,Manuela Banciu,Laurian VLase,Alina Porfire

Improved pharmacokinetics and reduced side effects of doxorubicin therapy by liposomal co-encapsulation with curcumin

2019

Alina Sesarman
Dana Muntean
Bianca Abrudan
Lucia Tefas
Bianca Sylvester
Emilia Licarete
Valentin-Florian Rauca
Lavinia Lupuţ
Laura Pătraş
Manuela Banciu
Laurian VLase
Alina Porfire

AbstractThe goal of the current study was to investigate the pharmacokinetic profile, tissue distribution and adverse effects of long-circulation liposomes (LCL) with curcumin (CURC) and doxorubici...

Keywords:

Chemistry
Liposome
Pharmacology
Chromatography
Curcumin
Doxorubicin
Biodistribution
Adverse effect
Encapsulation (computer programming)
Pharmacokinetics
Biochemistry
Colorectal cancer
Antioxidant

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