High-Throughput and Label-Free Detection of Motile Parasites in Bodily Fluids Using Lensless Time-Resolved Speckle Imaging

Yibo Zhang,Hatice Ceylan Koydemir,Michelle M. Shimogawa,Sener Yalcin,Alexander Guziak,Tairan Liu,Ilker Oguz,Yujia Huang,Bijie Bai,Yilin Luo,Yi Luo,Zhensong Wei,Hongda Wang,Vittorio Bianco,Bohan Zhang,Rohan Nadkarni,Kent L. Hill,Aydogan Ozcan

High-Throughput and Label-Free Detection of Motile Parasites in Bodily Fluids Using Lensless Time-Resolved Speckle Imaging

2019

Yibo Zhang
Hatice Ceylan Koydemir
Michelle M. Shimogawa
Sener Yalcin
Alexander Guziak
Tairan Liu
Ilker Oguz
Yujia Huang
Bijie Bai
Yilin Luo
Yi Luo
Zhensong Wei
Hongda Wang
Vittorio Bianco
Bohan Zhang
Rohan Nadkarni
Kent L. Hill
Aydogan Ozcan

We present a lensless time-resolved speckle imaging technique for label-free, sensitive and rapid detection of motile parasites in bodily fluids, by using the locomotion of parasites as a biomarker and contrast mechanism. © 2019 The Author(s)

Keywords:

Optics
Optoelectronics
Speckle imaging
Physics
Throughput
rapid detection
label free
Light scattering

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