Insights from engineering the Affibody-Fc interaction with a computational-experimental method

Masoumeh Nosrati,Sara Marie Øie Solbak,Olle Nordesjö,Mikael Nissbeck,Daniel F. A. R. Dourado,Ken G. Andersson,Mohammad Reza Housaindokht,John Löfblom,Anders Virtanen,U. Helena Danielson,Samuel C. Flores

Insights from engineering the Affibody-Fc interaction with a computational-experimental method

2017

Masoumeh Nosrati
Sara Marie Øie Solbak
Olle Nordesjö
Mikael Nissbeck
Daniel F. A. R. Dourado
Ken G. Andersson
Mohammad Reza Housaindokht
John Löfblom
Anders Virtanen
U. Helena Danielson
Samuel C. Flores

The interaction between the Staphylococcal Protein A (SpA) domain B (the basis of the Affibody) molecule and the Fc of IgG is key to the use of Affibodies in affinity chromatography and in potentia ...

Keywords:

Affinity chromatography
Biochemistry
Molecule
Biology
Protein A
Surface plasmon resonance
Protein–protein interaction
staphylococcal protein

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