Mogroside, palatinose, erythritol, and xylitol differentially affect dental plaque pH in caries-active and caries-free children: An in vitro study

Abstract Objective To investigate the effect of mogroside, palatinose, erythritol, and xylitol on the dental plaque pH of children and to compare the plaque pH change between caries-active and caries-free children caused by these sweeteners. Methods Thirty-six children (mean age 6.2 ± 2.9-year-old), caries-active and caries-free, were included. After refraining from practicing oral hygiene, the accessible plaque was collected and equally divided for challenging with 6 different solutions: mogroside, palatinose, erythritol, xylitol, 10% sucrose, and deionized water. The pH of each solution was measured using a digital pH meter at 0, 5, 10, 15, 20, 25, and 30 min. Results Mogroside, erythritol, xylitol, and water did not significantly lower the dental plaque pH, however, palatinose reduced dental plaque pH comparable to sucrose (p  Conclusions Mogroside, erythritol, and xylitol did not lower the dental plaque pH in caries-active or caries-free children. However, palatinose affected the dental plaque pH similar to sucrose.