Late Stage Fe(CO)5 Promoted Double Bond Migration: Total Synthesis of Limazepines C and D

Abstract The first total syntheses of limazepines C and D were accomplished from inexpensive and readily available starting materials using an iron pentacarbonyl promoted allylamide–enamide double bond migration as a key step. The obtained limazepine C was found to be unstable and undergoes oxidation to limazepine D.