Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug–Drug Interaction Potentials

Su-jin Rhee,Hyun-Ah Lee,So-Young Lee,Eunwoo Kim,Inseung Jeon,Im-Sook Song,Kyung-Sang Yu

Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug–Drug Interaction Potentials

2018

Su-jin Rhee
Hyun-Ah Lee
So-Young Lee
Eunwoo Kim
Inseung Jeon
Im-Sook Song
Kyung-Sang Yu

Purpose To build a physiologically based pharmacokinetic (PBPK) model for fimasartan, amlodipine, and hydrochlorothiazide, and to investigate the drug–drug interaction (DDI) potentials.

Keywords:

Fimasartan
Hydrochlorothiazide
Physiologically based pharmacokinetic modelling
Drug-drug interaction
Amlodipine
Chromatography
Chemistry
Pharmacokinetics
pharmacokinetic modeling
Pharmacology
Drug

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations