Chemical composition and antimicrobial activity of extracts from Gliocladium sp. growing wild in Tunisia

The chemical composition of chloroformic, ethyl acetate, butanolic, and methanolic extracts isolated from the fungus Gliocladium sp. using different solvents of increasing polarity was analyzed by GC-FID and GC-MS. Furthermore, the antimicrobial activity of extracts was tested against five Gram-positive and Gram-negative bacteria and four pathogenic fungi. The tested extracts exhibited an interesting antibacterial activity against all bacteria tested, even against Gram-negative bacteria presenting frequently a higher resistance and against all fungi except Candida albicans.