Synthesis process of sucralose-6-acetate

2016 
The invention discloses a synthesis process of sucralose-6-acetate. The synthesis process is characterized by mainly comprising the following steps: (1) preparing saccharose-6-acetate by adopting an enzyme-chemical method; (2) preparing a Vilsmeier reagent; (3) reacting the saccharose-6-acetate and the Vilsmeier reagent to generate the sucralose-6-acetate. According to the synthesis process, the saccharose-6-acetate is prepared by the enzyme-chemical method, so that the steps are simple, and the environment cannot be polluted; due to the direct reaction, which is retained at the optimal state by adjusting the pH, between the saccharose-6-acetate and the Vilsmeier reagent, the yield of the sucralose-6-acetate is increased, the reaction duration is shortened, and the cost is saved.
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