trans‐Hexahydrobenzoxazolidinones in the Enantioselective Synthesis of β2‐Amino Acids Containing Proteinogenic Side Chains.

The use of enantiopure trans-hexahydrobenzoxazolidinones as chiral auxiliaries in the enantioselective synthesis of two β2-amino acids containing proteinogenic side chains (β2-hPhenylalanine and β2-hLysine), in both enantiomeric forms, is described. Absolute configurations were assigned on the basis of X-ray diffraction analysis and chemical correlation methods.