Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

Jessika Bertacchini,Marianna Guida,Benedetta Accordi,Laura Mediani,Am Martelli,Patrizia Barozzi,Emanuel F. Petricoin,Lance A. Liotta,Gloria Milani,Marco Giordan,Mario Luppi,Fabio Forghieri,A. De Pol,Lucio Cocco,G Basso,Sandra Marmiroli

Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

2014

Jessika Bertacchini
Marianna Guida
Benedetta Accordi
Laura Mediani
Am Martelli
Patrizia Barozzi
Emanuel F. Petricoin
Lance A. Liotta
Gloria Milani
Marco Giordan
Mario Luppi
Fabio Forghieri
A. De Pol
Lucio Cocco
G Basso
Sandra Marmiroli

Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis

Keywords:

Protein kinase B
Cancer research
Myeloid leukemia
PI3K/AKT/mTOR pathway
Phosphorylation
mTORC2
RPTOR
Cell biology
Signal transduction
Apoptosis
Biology
Growth factor receptor
Tyrosine kinase

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