Ne wLif ei na nOl dIdea :Th eSynapti cPlasticit yand Memor yHypothesi sRevisited

Th enotio ntha tchange si nsynapti cefficac yunderlie learnin gan dmemor yprocesse si sno wwidel yaccepted ,althoug hdefin- itiv eproo fo fth esynapti cplasticit yan dmemor yhypothesi si sstil llacking. Thi sarticl ereview srecen tevidenc erelevan tt oth ehypothesis ,with particula remphasi so nstudie so fexperience-dependen tplasticit yi nthe neocorte xan dhippocampus .I nou rview ,ther ei sno wcompellin gevi- denc etha tchange si nsynapti cstrengt hoccu ra sa consequenc eo fcertain form so flearning .A majo rchalleng ewil lb et odetermin ewhethe rsuch change sconstitut eth ememor ytrac eitsel fo rpla ya les sspecifi csupport- in grol ei nth einformatio nprocessin gtha taccompanie smemor yforma- tion .Hippocampu s2002;12:60 9- 636 . ©200 2Wiley-Liss ,Inc. KE YWORDS: LTP ;LTD ;learning ;hippocampus ;cortex