Insensitivity of dispersed caprine luteal cells to β-adrenergic agonists and other putative transmitter substances

Abstract Adrenaline (10 −6 –10 −4 M), serotonin (10 −6 –10 −4 M), and several other potential steroidogenic agonists failed to enhance either basal or LH-stimulated progesterone production from dispersed caprine luteal cells from Day 10 of the estrous cycle. The caprine corpus luteum (CL) would appear to be more refractory to exogenous stimulation than either the ovine or bovine CL.