Photodynamic Therapy of Skin using Porphyrin Precursors: Optical Monitoring, Vascular Effects and Personalized Medicine
2014
markdownabstract__Abstract__
Photodynamic therapy (PDT) is based on a photochemical reaction that involves three
basic components: (1) a photosensitizer, which is a light-sensitive molecule that mediates
transfer of light energy to molecular oxygen; (2) light of the appropriate wavelength
that is absorbed by the photosensitizer, and (3) molecular oxygen. These components
interact with each other and with the surrounding tissue, creating the photodynamic
effect. The photodynamic processes are based on quantum mechanical principles that
are described below and schematically illustrated in figure 1.
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