New Therapy for Ocular Surface Disorders on the Horizon - Prosthetic Replacement of the Ocular Surface Ecosystem: A Review Article

Introduction: Prosthetic replacement of the ocular surface ecosystem (PROSE) has been a major innovation in the management of ocular surface disorders. It is a prosthetic device almost similar to a contact lens, designed for the purpose of daily wear. It creates a transparent, smooth optical surface over the damaged cornea. Furthermore, it has an expanded artificial tear reservoir that provides constant lubrication while maintaining the necessary oxygen supply. It has been proposed as management for ocular surface disorders against invasive procedure like keratoplasty. Several clinical studies have come forward with promising results. Limitations of PROSE include high cost and reduced access.