CRIF1 Interacting with CDK2 Regulates Bone Marrow Microenvironment-Induced G0/G1 Arrest of Leukemia Cells

Qian Ran,Ping Hao,Yanni Xiao,Lixing Xiang,Xingde Ye,Xiaojun Deng,Jiang Zhao,Zhongjun Li

CRIF1 Interacting with CDK2 Regulates Bone Marrow Microenvironment-Induced G0/G1 Arrest of Leukemia Cells

2014

Qian Ran
Ping Hao
Yanni Xiao
Lixing Xiang
Xingde Ye
Xiaojun Deng
Jiang Zhao
Zhongjun Li

Background To assess the level of CR6-interacting factor 1 (CRIF1), a cell cycle negative regulator, in patients with leukemia and investigate the role of CRIF1 in regulating leukemia cell cycle.

Keywords:

Jurkat cells
Bone marrow
Cell cycle
Regulator
Leukemia
Cell biology
Cell Cycle Protein
Leukemia inhibitory factor
Cyclin
Biology
Cyclin-dependent kinase 2

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