(−)-Salzol, an isopimarane diterpene, and a chalcone from Hyptis salzmanii

Abstract From the leaves of Hyptis salzmanii a new isopimarane diterpene, named (−)-salzol, and the new 4,2′,6′-trihydroxy-4′-methox,ychalcone were isolated, together with three known lignans, i.e. (+)-sesamin, (−)-cubebins, (−)-hinokinin, three known flavanones, i.e. (−)-isosakuranetin, (±)-sakuranetin, (+)-naringenin-7,4′-dimethylether, and p -methoxycinnamic acid. The structure of 20-benzoyloxy-6β,7β,8β,9α-tetrahydroxyisopimar-15-ene, assigned to (−)-salzol, and the structure of the chalcone were determined on the basis of chemical and spectral data.