Data driven time alignment for TOF-PET

The accuracy of joint reconstruction methods using time of flight (TOF) positron emission tomography (PET) data, highly depends on an accurate model of the TOF measurements. In this contribution we consider the relative positioning of the TOF data-bins along each line of response (LOR) from TOF-PET emission data. Similar to an existing data-driven method, we assume that any shifts of TOF data-bins along lines of response can be modelled as differences between crystal timing offsets. Results are shown with and without accounting for the estimated TOF shifts for phantom and patient brain scans.