Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57−KIR−NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57−KIR−NKG2A− NK Cells

Elin Forslund,Ebba Sohlberg,Monika Enqvist,Per E. Olofsson,Karl-Johan Malmberg,Björn Önfelt

Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57−KIR−NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57−KIR−NKG2A− NK Cells

2015

Elin Forslund
Ebba Sohlberg
Monika Enqvist
Per E. Olofsson
Karl-Johan Malmberg
Björn Önfelt

NK cells are functionally educated by self-MHC specific receptors, including the inhibitory killer cell Ig-like receptors (KIRs) and the lectin-like CD94/NKG2A heterodimer. Little is known about ho ...

Keywords:

Cell
Lymphokine-activated killer cell
Immunology
Interleukin 21
NK Cell Lectin-Like Receptor Subfamily C
Biology
HEK 293 cells
Molecular biology
Receptor
Flow cytometry
Cell biology
Interleukin 12
Inhibitory postsynaptic potential

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