Investigating the effects of ebselen, a potential new lithium mimetic, on glutamate transmission

Filipa Mota,Teresa Sementa,Carlotta Taddei,Natasha Moses,Jayanta Bordoloi,Stefan Hader,Thomas R. Eykyn,Diana Cash,Federico Turkheimer,Mattia Veronese,Nisha Singh

Investigating the effects of ebselen, a potential new lithium mimetic, on glutamate transmission

2020

Filipa Mota
Teresa Sementa
Carlotta Taddei
Natasha Moses
Jayanta Bordoloi
Stefan Hader
Thomas R. Eykyn
Diana Cash
Federico Turkheimer
Mattia Veronese
Nisha Singh

Ebselen, a potential new lithium-like drug, treatment reduced brain glutamate, as measured by PET imaging using the mGluR5 radioligand [(18) F]FPEB in rats.

Keywords:

Glutamate receptor
Lithium
Psychology
Ebselen
Endocrinology
Pharmacology
Internal medicine
Metabotropic glutamate receptor 5
pet imaging
Radioligand

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