Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons

A.K. Goodwin,P. R. Brown,Erwin E.W. Jansen,C. Jakobs,Km Gibson,Elise M. Weerts

Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons

2009

A.K. Goodwin
P. R. Brown
Erwin E.W. Jansen
C. Jakobs
Km Gibson
Elise M. Weerts

Rationale Gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) are prodrugs for gamma-hydroxybutyrate (GHB). Like GHB, GBL and 1,4-BD are drugs of abuse, but their behavioral effects may differ from GHB under some conditions.

Keywords:

1,4-Butanediol
Anesthesia
Internal medicine
Endocrinology
Gamma hydroxybutyrate
gamma-Butyrolactone
Conditioning operant
Psychology
Pharmacology
Prodrug
4-Butyrolactone
Pharmacokinetics
drugs of abuse
pharmacology toxicology

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations