Efficient ring-closure approach via copper-catalyzed reactions of sulfonyl azide, terminal alkynes and alcohols/amines
2007
We have developed a general and efficient method for synthesis of medium- and large-sized heterocycles via copper-catalyzed reactions of sulfonyl azide, terminal alkynes (or bisalkyne) and alcohols/amines (diamines) at room temperature, and the highly practical method provides an entry toward diverse medium- and large-sized heterocycles.
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