Abstracts Book : XXVI - SILAE 2017 Società Italo-Latinoamericana di etnomedicina y IX Congreso colombiano de cromatografía – COCOCRO 2017

El presente documento recoge 2 investigaciones realizadas en modo “Oral communications” y 11 en modo “Poster” presentadas para el congreso XXVI– SILAE 2017 Societa Italo-Latinoamericana di etnomedicina y IX Congreso colombiano de cromatografia – COCOCRO 2017; realizado en Cartagena. Estos resumenes recogen la investigacion sobre la leishmaniasis y el desarrollo de fitomedicinas basadas en plantas, que permitan tratar la esta condicion y sus manifestaciones como medicinas alternativas, que sean efectivas y a bajo costo. Los trabajos presentados fueron: “Oral communications”: (1) Cytotoxicity and leishmanicidal activity of essential oil from plants present in Colombia and commonly used in traditional medicine; (2) Studies in vitro and in vivo of antileishmanial activity and differential cytotoxicity of Cannabis spp. En modo “Poster” (1) Phytochemistry and ethnopharmacological research on isla grande, Cartagena; (2) Ethnobotanical study of medicinal plants in Isla Grande, Cartagena Colombia; (3) In vitro evaluation of interaction of anti-inflammatory, wound healing and anti-leishmanial activities. An useful strategy to identify hit compounds for drug development to treat cutaneous leishmaniasis; (4) Chemical composition and evaluation of the biological potential of three vegetable species of the caribbean region; (5) Characterization by means of gas chromatography / mass spectrometry (gc / ms) and evaluation of the antibacterial activity of the essential oil of the bark from Astronium graveolens; (6) Synthesis and trypanocide activity of chloro and bromo l-tyrosine derivatives; (7) Leishmanicidal and citotoxic activity of benzothiopyrans. Structure-activity relationship; (8) Chemical composition, antioxidant activity, antimicrobial and antiprotozoal properties of ethanol propolis extracts of Bolivia; (9) Leishmanicidal activity and cytotoxicity in vitro of styrylquinolines; (10) Antileishmanial activity of rich fractions in alkaloid and flavonoid to design and develop a new low cost topical phytomedicine product from medicinal plants in the northern coast of Colombia; (11) Synthesis, leishmanicidal activity and chiral resolution of 4-oxothiochromane-2-carboxylic acid and its esters and amides derivatives.