Burden and Determinants of Chronic Kidney Disease Among Diabetic Patients in Ethiopia: A Systematic Review and Meta-Analysis

2021 
Background: Chronic kidney disease (CKD) among diabetic patients is becoming a global health burden and the incidence is high in low-income countries. In Ethiopia, there is no national representative evidence; therefore, this review aimed to estimates the pooled burden of CKD among patients with diabetes. Methods: Published and unpublished articles from various electronic databases were accessed. We included all observational studies in the review. A random-effects model was used to estimate the pooled estimate with a 95% confidence interval (CI). Results: Published (297) and unpublished (2) literature were identified from several databases and digital libraries, of which twelve articles were selected for final meta-analysis. The analysis found that the pooled burden of CKD among patients with diabetes was 18.22 %. Factors such as hypertension, type of DM, and duration of DM were found to have significant association with CKD. Conclusion: The current review revealed a higher burden of CKD among patients with diabetes in Ethiopia. For better control of chronic kidney disease, integrated management of hypertension and DM should be designed with a special focus on chronic diabetic patients.
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