A study of surface plasmon resonance (SPR) based biosensor with improved sensitivity

Abstract In the present study, surface plasmon resonance (SPR) based biosensor with SF-10 glass prism/zinc oxide/gold/MoS 2 /graphene hybrid structure is reported. The angular interrogation method is used for the reflectance spectra analysis. From the spectral analysis, we study the different performance parameters like sensitivity, detection accuracy, quality parameter and electric field intensity enhancement factor (EFIEF) of the proposed SPR based biosensor. Numerical results show that the base ZnO (zinc oxide) layer which have a large real value of the dielectric constant in combination with gold, MoS 2 and graphene, is responsible for enhancing the sensing performance of the proposed SPR based biosensor. The present biosensor can attain a maximum sensitivity (101.58 deg/RIU), detection accuracy (1.81) and quality parameter (15.11 RIU -1 ) for a large dynamic range of refractive index change from 1.33 to 1.45.