Registro, clasificación y estudio de imágenes digitalizadas de resonancia magnética del cerebro humano (Cuarta parte): Obtención de valores de ángulos en imágenes de resonancia magnética de cerebros como complemento al estudio de modificaciones cerebrales

In several meetings of the Sociedad Argentina de Investigacion Clinica, we showed in parasagittalmagnetic resonance imaging (IPRM) that with increasing age the surface of the prefrontal lobe(SLPF) is reduced; the surface of the corpus callosum (SCC) is also reduced (Merlo et al Rev ChilAnat 2002; 20: 131-138).The objective is to quantify in magnetic resonance imaging of both sexes, the variation of SLPF/ SCC ratio with advancing age. In IPRM equidistant 4mm midsagittal plane of 64 male and 65female subjects without diagnosis of mental or neurological disease, were measured with the ScionImage program for Windows SCC and in the same picture, the SLPF between the leading edge ofbrain and perpendicular to the line passing through the most distant parts of the corpus callosumventral edge at its intersection with the dorsal edge of the genu. For each case hemisphere SLPF/ SCC ratio was calculated. Relations were grouped by gender, age ranges (21-40, 41-60 and 61-84 years) and hemisphere and means were calculated +/- ES. For statistical analysis ANOVA wasused. The Pearson correlation coefficient (r) between age (21-84 years) and values SLPF / SCCeach hemisphere was determined for each sex. The SLPF / SCC relationships (mean +/- ES) rightand left on the male and female group are significantly lower (p <0.01 ANOVA) with increasingage ranges. Pearson’s r (p <0.01) between age (21-84 years) and SLPF / SCC right and left in thefemale group are -0.65 and -0.62 and -0.61 and -0.60 male, indicating inverse correlation betweenvariables. The significant decrease with increasing age in both sexes of the relationship between thesurface corresponding to the prefrontal lobe (measured between reliable anatomic landmarks) andthe surface of the corpus callosum in the very image of each hemisphere is indicative of the lobesurface prefrontal is the most severely impaired relative.