Chemopreventive effects of silymarin against 1,2-dimethylhydrazine plus dextran sodium sulfate-induced inflammation-associated carcinogenicity and genotoxicity in the colon of gpt delta rats.

Division of Genetics and Mutagenesis, National Institute of Health Sciences, Tokyo 158-8501, Japan, Department of Oncologic Pathology, Kanazawa Medical University, Ishikawa 920-0293, Japan, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan, Department of Physiology and Nutrition, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido 069-8501, Japan and The Tokai Cytopathology Institute: Cancer Research and Prevention, Gifu 500-8285, Japan