Pyridine-3-carboxamides as novel CB 2 agonists for analgesia
2009
Abstract We describe herein the medicinal chemistry approach which led to the discovery of a novel pyridine-3-carboxamide series of CB 2 receptor agonists. The SAR of this new template was evaluated and culminated in the identification of analogue 14a which demonstrated efficacy in an in vivo model of inflammatory pain.
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