Medical 15O production via the 16O(γ,n)15O reaction for blood flow examination

We propose a new scheme for producing medical 15O isotopes using a water target, for blood flow examination with Positron Emission Tomography. The 15O radioisotopes are produced via the 16O(γ,n)15O reaction in a water target. A simulation study has been carried out to determine the productivity of radioactive [15O]-water using bremsstrahlung γ–rays by a 40 MeV electron beam of 100 μA. The productivity of [15O]-water with an activity of 6.9 GBq was confirmed by a 10-min radiation exposure. Produced [15O]-water is easily and rapidly sent from the production site to a patient site through a transport tube.