Progressive Reticulated Pigmentation of the Folds

Dowling-Degos Disease is a rare reticulated pigmented anomaly, recently considered as autosomal dominant genodermatosis, characterized by a reticulate pattern of abnormally hyperpigmentations, usually affecting the body folds and creases. First discovered by Dowling and Freudenthal in 1938, the disease is later described by Degos and Ossipowski in 1954, as Reticulated pigmentary dermatosis of the folds. Differential diagnosis includes a wide spectrum of reticulate pigment disorders of the skin.