Seminal Vesicle Carcinoma-In-Situ in An Adult Rhesus Macaque: A Case Report and Review of The Literature

A seminal vesicle carcinoma-in-situ was diagnosed as an incidental finding during histopathological evaluation of necropsy tissues in a 9 year old intact male Indian origin Rhesus macaque.  The animal had been used in a series of infectious disease studies and in a terminal renal transplantation experiment over the course of its life at the Armed Forces Research Institute of Medical Sciences.  Diagnosis was proffered by a board certified (ACVP) veterinary pathologist due to the microscopic appearance of the neoplasm and confirmed using immunohistochemistry.  This report represents the first description of a seminal vesicle carcinoma-in-situ in a non-human primate.