N-Iodosuccinimide-Mediated Dimerization of 2-Alkynylnaphthols: A Highly Diastereoselective Construction of Bridged Polycyclic Compounds via Vinylidene ortho-Quinone Methide Intermediate.

Yu Tan,Zhengxing Zhao,Zhili Chen,Shengli Huang,Shiqi Jia,Lei Peng,Da Xu,Wenling Qin,Hailong Yan

N-Iodosuccinimide-Mediated Dimerization of 2-Alkynylnaphthols: A Highly Diastereoselective Construction of Bridged Polycyclic Compounds via Vinylidene ortho-Quinone Methide Intermediate.

2020

Yu Tan
Zhengxing Zhao
Zhili Chen
Shengli Huang
Shiqi Jia
Lei Peng
Da Xu
Wenling Qin
Hailong Yan

An unprecedented highly diastereoselective dimerization of 2-alkynylnaphthols is presented to furnish bridged polycyclic compounds containing a bicyclo[3.2.1]octane moiety with good to excellent yi...

Keywords:

Organic chemistry
Quinone methide
Medicinal chemistry
Moiety
Octane
Bicyclic molecule
N-iodosuccinimide
Chemistry

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