Approaches to Rapid In Vivo Optimization of Hydrophilic Matrix Tablets
2014
The optimisation of hydrophilic matrix tablets to balance formulation, biopharmaceutical, and physiological variables to achieve a target product profile is a complex process. Traditionally this optimisation process has relied upon application of a series of in vitro, preclinical, and clinical experimentation which extend programme timelines and increase cost to the development programme.
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