Palmitoylcarnitine, and important component of the repair system in the synaptosome membrane, in oxidative stress

Oxidative stress is accompanied by a considerable rise of palmitic acid incorporation into phosphatidylethanolamine of synaptosome membranes due to activation of lysophosphatidylethanolamine palmitoyltransferase and carnitine palmitoyltransferase. In the absence of ATP carnitine palmitoyltransferase plays an essential role in reacylation of phosphatidylethanolamine, and palmitoylcarnitine serves as a reserve pool of palmitoyl coenzyme A.