Amyloidosis due to TTR mutations in Mexico with 4 distincts genotypes in the index cases

Background Transthyretin-related hereditary amyloidosis (ATTR) is a systemic disease characterized by extracellular deposits of amyloid due to the autosomal dominant inheritance of a mutation in the TTR gene (18q12.1). Although described worldwide, it is a rare disease, limited to certain parts of the world. The aim of this manuscript is to describe the presence and characteristics of ATTR in Mexico.