Biological activity of the protein complex from soy meal

The amino-acid composition of the active fraction of a protein complex was determined. An analysis of the N-terminal amino acids found threonine, glycine, serine, proline, and valine at N-terminuses. The protein complex at a dose of 100 g/mL suppressed incorporation of 14 C-thymidine marker by 64.0 ± 1.9% in a radiometric cytotoxicology test for KML murine melanoma cell proliferation. The protein complex contained protease inhibitors, inhibited the growth of tumor strain AKATON by greater than 60%, and did not inhibit bone marrow cell proliferation.