Digital adaptive optics based on digital lateral shearing of the computed pupil field for flying spot retinal swept source OCT in vivo

A novel non-iterative digital adaptive optics (DAO) technique is presented in which the wavefront error is calculated using the phase difference between the pupil field and its digital copies translated by a pixel along the horizontal and vertical direction of the defined co-ordinate of the pupil plane. Using this method, a large wavefront error with peak to valley of 20 radians and RMS error of 0.71 waves is detected and corrected in case of a micro-beads phantom sample. Also, human photoreceptor image is recovered from an aberrated retinal OCT acquired at the eccentricity of 2 degrees from fovea in-vivo with a flying spot OCT system using a phase stable akinetic swept source at 1060 nm.