Study on the cytotoxic and genotoxic capacity of decoctions of Minthostachys verticillata from Córdoba, Argentina.

INTRODUCTION The popular use of medicinal plants is an ancient practice, and even widespread used all over the world. Among the bioactivities of interest are the evaluation studies on the cyto-genotoxic potential of such plants (Rani et al., 2005). Minthostachys verticillata (Griseb) Epling. (‘peperina’) is an example of a commonly used plant in the popular medicine of Cordoba, Argentina. Infusions are indicated for treatment of indigestions, vomits, stomach pains, owing to the digestive, carminative and antispasmodic properties (Cantero and Nunez, 2000). Fractions of peperina extracts have been proved in a number of in vitro assays, and their immunomodulator, antimicrobial and antiviral action has been demonstrated (Zanon et al., 1999; Escobar et al., 2004). The aim of this study was to determine the effect of decoctions of this plant species on chromosomes and cell cycle by the Allium cepa L. test.