Suppression of cell migration is promoted by miR-944 through targeting of SIAH1 and PTP4A1 in breast cancer cells

Ali Flores-Pérez,Laurence A. Marchat,Sergio Rodríguez Cuevas,Verónica Bautista,Lizeth Fuentes-Mera,Diana Romero-Zamora,Anabel Maciel-Dominguez,Olga Hernández de la Cruz,Miguel Fonseca-Sánchez,Erika Ruiz-García,Horacio Astudillo-de la Vega,César López-Camarillo

Suppression of cell migration is promoted by miR-944 through targeting of SIAH1 and PTP4A1 in breast cancer cells

2016

Ali Flores-Pérez
Laurence A. Marchat
Sergio Rodríguez Cuevas
Verónica Bautista
Lizeth Fuentes-Mera
Diana Romero-Zamora
Anabel Maciel-Dominguez
Olga Hernández de la Cruz
Miguel Fonseca-Sánchez
Erika Ruiz-García
Horacio Astudillo-de la Vega
César López-Camarillo

Background Aberrant expression of microRNAs has been associated with migration of tumor cells. In this study, we aimed to investigate the biological significance of miR-944 whose function is unknown in breast cancer.

Keywords:

Cancer research
Breast cancer
Pathology
Cell migration
microRNA
SIAH1
Surgical oncology
Immunology
Biology
PRKCA Gene
actin cytoskeleton
Viability assay
Gene silencing
RNA interference

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