Cobalt-catalyzed oxidative arylmethylation of phosphorylamides

Abstract A cobalt-catalyzed strategy for N -arylmethylation of phosphorylamides was herein achieved with the assistance of azodiisobutyronitrile as the radical initiator and di- tert- butyl peroxide as the oxidant. Both methylarenes and diaryl methanes were compatible under the oxidative conditions, expressing broad substrate scope (51 examples) and high efficiency (up to 87% yield).