Differential Microglial Morphological Response, TNFα, and Viral Load in Sedentary-like and Active Murine Models After Systemic Non-neurotropic Dengue Virus Infection

Giovanni Freitas Gomes,Railana Deise da Fonseca Peixoto,Brenda Gonçalves Maciel,Kedma Farias dos Santos,Lohrane Rosa Bayma,Pedro Alves Feitoza Neto,Taiany Nogueira Fernandes,Cintya Castro de Abreu,Samir Mansour Moraes Casseb,Camila M. de Lima,Marcus A. de Oliveira,Daniel Guerreiro Diniz,Pedro Fernando da Costa Vasconcelos,Marcia Consentino Kronka Sosthenes,Cristovam Wanderley Picanço Diniz

Differential Microglial Morphological Response, TNFα, and Viral Load in Sedentary-like and Active Murine Models After Systemic Non-neurotropic Dengue Virus Infection

2019

Giovanni Freitas Gomes
Railana Deise da Fonseca Peixoto
Brenda Gonçalves Maciel
Kedma Farias dos Santos
Lohrane Rosa Bayma
Pedro Alves Feitoza Neto
Taiany Nogueira Fernandes
Cintya Castro de Abreu
Samir Mansour Moraes Casseb
Camila M. de Lima
Marcus A. de Oliveira
Daniel Guerreiro Diniz
Pedro Fernando da Costa Vasconcelos
Marcia Consentino Kronka Sosthenes
Cristovam Wanderley Picanço Diniz

Peripheral inflammatory stimuli increase proinflammatory cytokines in the bloodstream and central nervous system and activate microglial cells. Here we tested the hypothesis that contrasting enviro...

Keywords:

Molecular biology
Biology
Virology
Tumor necrosis factor alpha
Viral load
Dengue virus
Stimulus (physiology)
Environmental enrichment
Immunology
Proinflammatory cytokine
Central nervous system

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