Investigation of Anthelmintic and Insecticidal activity of Goniothalamus sesquipedalis plant in different extracts

Within different extract of Goniothalamus sesquipedalis the evaluation of anthelmintic and insecticidal activity conducted in present studies. For anthelmintic activity, selected animal was Pheretima posthuma for testing while 25, 50, 100 mg/ml concentrations of specimen were tested in the bioassay, from which time of paralysis and time of death of worms were estimated. Assay of insecticidal action was executed against Sitophilus oryzae to assess the mortality rate. MEE, EE, ACE, CHE, PEE and NHE extract were there for the activity determination. In anthelmintic study, extract exhibition and activity in dose-dependent manner showing higher the concentration, faster the effect. Extract of EE, PEE, CHE and MEE in case of 100 mg/ml concentration showed its paralytic effect followed by death within a short period of time among which EE extract gave the best result which only took approx. 22.33 minutes to show paralytic effect and 33 minutes for death occurrence. In insecticidal activity, all extracts showed efficacious activity with 100% mortality of rice insects Sitophilus oryzae at 80 mg/ml concentration in 24hrs, proving the activity also followed dose dependent pattern. 80% mortality rate observed in case of 80 mg/ml concentration of ACE extract in 12 hr whereas MEE, CHE and NHE extracts showed 60 % and PEE showed 70% mortality rate in treated rice insects. The present study shows that all the extracts of Goniothalamus sesquipedalis are found to retain anthelmintic and insecticidal activities.