Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemia.

PAX5 encodes for a transcription factor essential for B-lymphoid cell commitment and is rearranged in 30% of B-cell precursor acute lymphoblastic leukemia pediatric patients (BCP-ALL).[1][1] Since the first characterization of PAX5/ETV6 ,[2][2] an increasing number of PAX5 fusion genes have been