Network-wide oscillations in the parkinsonian state: alterations in neuronal activities occur in the premotor cortex in parkinsonian nonhuman primates

This study begins to fill a gap in knowledge regarding how Parkinson’s disease (PD) may cause abnormal functioning of the premotor cortex. It is novel as the premotor activity is examined in both the naive and parkinsonian states, in the same subjects, at the single unit and local field potential level. It provides foundational knowledge on which to build future studies to explore the relationships between premotor activities and specific parkinsonian motor and cognitive deficits.