Urease Inhibitiory Flavone Glucosides from Marrubium anisodon

Compounds 1-3, new flavonoid glucosides have been isolated from the ethyl acetate soluble fractions of Marrubium anisodon, along with apigenin 4'-O-β-D-glucopyranoside 4, kaempferol 3-O-β-D-glucopyranoside 5 and β-sitosterol 3-O-β-D-glucopyranoside 6, respectively. Their structures were assigned from 1 H- and 13 C-NMR spectra, DEPT and by COSY, HMQC, NOESY and HMBC experiments. Compounds 1-5 showed significant inhibitory activity against the enzyme urease.