Lo EH (2006) Involvement of matrix metalloproteinase in neuroblast cell migration from the subventri

A method for the prophylaxis or treatment of thromboses in humans which comprises administering to a human in need thereof a therapeutically effective amount of a compound of the formula (II) (II) or a pharmaceutically acceptable acid addition salt thereof, wherein R is 1-piperidyl or 1-pyrrolidyl. Compounds of the formula (II) are also useful for the inhibition of platelet aggregation in vitro or in vivo.