Model-based reconstructive approaches in optical coherence elastography of ocular tissues

The biomechanical characteristics of ocular tissues have a profound influence on the normal function of the human eye. We have developed noninvasive optical coherence elastography approaches to measure elastic properties of the ocular tissues. Biomechanical properties are evaluated based on developed mathematical models of the dynamic deformation of the viscoelastic medium. We have demonstrated the influence of such factors as age and intraocular pressure on the mechanical properties of the crystalline lens, cornea, and other tissues. The optical coherence elastography was demonstrated as a promising tool for noninvasive assessment of the biomechanical properties of the ocular and other tissues.