Re-crystallization of bioactive glass mixed with various hardening agents

Abstract Bioactive glass (BG) is a potential material for treating dentin hypersensitivity due to its high solubility. In this study, a commercial BG powder (PerioGlas®, PG) mixed with various hardening agents was applied in human dentinal tubule occlusions. X-ray diffraction (XRD), scanning electronic microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR) were used to investigate the re-crystallization behavior of human dentin and the dentinal tubule occlusion efficiency by mixing PG with various hardening agents. The major crystalline phases of PG mixed with phosphoric acid are CaHPO 4 ·2H 2 O and CaH 2 P 2 O 7 . PG mixed with 20 or 30 wt% phosphoric acid acted as a hardening agent and achieved a dentinal tubule penetration depth of 68–74 µm. PG mixed with suitable phosphoric acid agents has a short reaction time and a good operability that is feasible for occluding dentinal tubules. PG mixed with hardening agents has a greater potential for treating dentin hypersensitivity than PG without hardening agents.