HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation
2015
Apolipoprotein-M-bound sphingosine-1-phosphate (S1P) is found to restrain the generation of new lymphocytes—and, consequently, adaptive immune responses—by activating the S1P1 receptor on bone marrow lymphocyte progenitors in mice.
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