Epidemiology, risk, myths, pharmacotherapeutic management and socio economic burden due to novel COVID-19: A recent update

[ ]date there is not even a single drug or vaccine that can be used for the effective treatment for this disease The lung epithelial cells are the primary target of the virus because host cell is the first step of viral infection followed by the fusion with the cell membrane hence it has been reported that human to human transmission of SARS-CoV2 occurs by the binding between the receptor-binding domains of virus spikes with the cell, which has been identified as angiotensin-converting enzyme-2 (ACE2) receptor The sample should be stored in laboratory for the amplification of the genetic material extracted from the mucus or saliva sample is through a reverse transcription polymerase chain reaction (RT-PCR), which involves the synthesis of a double-stranded (ds) DNA molecule from an RNA The probes are taken on the initial gene sequence released by the Shanghai Public Health Clinical Centre & School of Public Health, Fudan University, Shanghai, China on Virological org, and subsequent confirmatory evaluation by other labs If the test result is positive, it is recommended that the test is repeated for verification [27]